{"product_id":"same-400mg","title":"SamE 400mg","description":"\u003cul\u003e •\u003cb\u003eSAMe helps maintain stable mood and joint function without side effects\u003c\/b\u003e. In addition, SAMe has multiple mechanisms of action that are used throughout the body, especially in the liver, which help maintain liver health. \u003cbr\u003e\n\n •Largely known for its effects on optimal mood, \u003cb\u003eSAMe has also shown benefits for the liver, brain, and joints\u003c\/b\u003e.\u003cbr\u003e\n\n •SAMe is an amino acid derivative normally synthesized in the body that may become depleted with sickness or age. Supplementing with SAMe plus folate, trimethylglycine (TMG or betaine), vitamins B6 and B12 appears to be an effective way to overcome this deficiency. \u003cbr\u003e\n\n •\u003cb\u003eSAMe is concentrated in the liver and brain\u003c\/b\u003e and is a major methyl donor in the synthesis of hormones, nucleic acids, proteins, and phospholipids, and catecholamines and other neurotransmitters. \u003cb\u003eSAMe is required for the synthesis of norepinephrine, dopamine, and serotonin\u003c\/b\u003e. SAMe facilitates glutathione usage, which improves the body's antioxidant defense. It also helps \u003cb\u003emaintain acetylcholine levels\u003c\/b\u003e which are necessary for cognitive function.\u003cbr\u003e\n\n •\u003cb\u003eSAMe's ability to boost brain cell methylation facilitates youthful DNA enzymatic actions which may help account for SAMe’s mood-elevating properties.\u003c\/b\u003e These enzymatic reactions are \u003cb\u003erequired for the healthy conversion of neurotransmitters such as serotonin and dopamine.\u003c\/b\u003e\n\u003c\/ul\u003e","brand":"Life Extension","offers":[{"title":"Default Title","offer_id":51614099144836,"sku":"LifeExt SamE 400mg 60t","price":52.49,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0950\/9758\/5796\/files\/img-27799-1003-1773331257956.jpg?v=1773331727","url":"https:\/\/shop.nutritionw.com\/products\/same-400mg","provider":"Nutrition World","version":"1.0","type":"link"}