Adenosylcobalamin helps preserve neuronal function
Leucine-Rich Repeat Kinase 2 (LRRK2) is a type of enzyme that modifies other proteins by adding phosphate groups. Inhibiting the activity of this enzyme has been associated with helping to preserve neuronal tissue.

A series of preclinical studies has shown that the adenosylcobalamin form of B12 can inhibit the activity of multiple LRRK2 variants in neurons by decreasing phosphorylation (the addition of phosphate groups to amino acids).

These studies found that adenosylcobalamin helped regulate healthy release of dopamine, a neurotransmitter that plays an important role in cognitive functions such as motor control, arousal, reinforcement and reward.

A cofactor for energy metabolism
Adenosylcobalamin is active in the mitochondria, the powerhouses of your cells. It’s required as a cofactor for the synthesis of succinyl-CoA, a compound that supports cellular energy metabolism.

Methylcobalamin for cellular health & beyond
Methylcobalamin is another neurologically active form of B12 (though in different ways than adenosylcobalamin). Methylcobalamin supports the central nervous system, and it’s essential for the replication and growth of cells.

Methylcobalamin helps to maintain already healthy homocysteine levels. Inhibiting excess levels of this compound is key to maintaining healthy cardiovascular and neurological function.

B12 for a healthy brain and more
This B12 formula combines methylcobalamin and adenosylcobalamin to offer optimal cognitive support. Want the health benefits of the full range of the B vitamins? We also offer our BioActive Complete B-Complex formula: a wide-spectrum of B vitamins for whole-body health.

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We want you to be confident in every purchase. If you are not satisfied with a product, we will work with you to find a fair solution.

Returns and Refunds

Unopened Products

• May be returned within 30 days of purchase for a full refund.
• Product must be in resalable condition.
• Original receipt or proof of purchase required.

Opened Products

• May be returned within 30 days if the product did not meet expectations.
• Refunds for opened products are limited to one return per product, per customer, within a 12-month period.
• Products that are substantially consumed (for example, more than 50% used) may not qualify for a refund.

Damaged or Incorrect Orders

If an item arrives damaged or you receive the wrong product:

• Contact us within 7 days of delivery.
• We will replace the item or issue a full refund, including shipping charges when appropriate.

Non-Returnable Items

The following items are not eligible for return:

• Clearance or closeout merchandise.
• Expired products due to customer storage.
• Gift cards.
• Products intentionally damaged or altered.
• Special-order items.

Shipping Charges

• Original shipping charges are non-refundable except when the error was ours.
• Customers are responsible for return shipping costs unless the product was damaged, defective, or shipped incorrectly.

Abuse Prevention

Nutrition World reserves the right to limit or refuse returns when there is evidence of excessive return activity, misuse of the policy, fraudulent behavior, or repeated returns of similar products.

How to Request a Return

Contact our customer service team with:

• Order number
• Product name
• Reason for return

Most requests will be reviewed within 2 business days.

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While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Actual product packaging and materials may contain more and/or different information than that shown on our Web site. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Nutrition World assumes no liability for inaccuracies or misstatements about products.Any items offered by Nutrition World are not intended to diagnose, treat, cure, or prevent any disease. Seek additional advice from a qualified health care provider.

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